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Description
ACNESOL 0.05% W/W CREAM
COMPOSITION
Acnesol contains Tretinoin B.P 0.05% w/w as the active ingredient.
PHARMACOLOGY
Tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells, causing extrusion of comedos. It also reduces hyperkeratinization that leads to microcomedo formation, which is the initial lesion in acne. In dermis blood vessel, vasodilation and angiogenesis and increased papillary dermal collagen synthesis lead to lessening of fine and course wrinkling, smoother texture and a decrease in hyperpigmentation.
PHARMACOKINETICS
Tretinoin is highly bound to plasma proteins and undergoes metabolism in the liver. It is excreted in the bile and urine.
Indicator
Acnesol is used for the treatment of the following:
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